DHED

DHED crystal 구조

 

Aricept와 DHED 비교

 

DHED reduced toxicity and memory impairment by Ab

 

---

DHED reduced toxicity and memory impairment by Aβ

 

DHED reduced neurotoxicity, cognitive impairment and neuronal death induced by APP-CTs

 

DHED decreased cytotoxicity in glutamate-treated primary neuronal cells and on MK-801 binding

 

---

DHED decreased sAPPb production in stably transfected HEK293 cell line expressing BACE

 

DHED decreased Neuronal loss in hippocampal formation of Tg2576 & Wt mice (12 months)

 

DHED increased Neurosphere numbers (neuronal stem cell) at 7days after DHED treatment